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Activity of Praziquantel Enantiomers and Main Metabolites against Schistosoma mansoni
A racemic mixture of R and S enantiomers of praziquantel (PZQ) is currently the treatment of choice for schistosomiasis. Though the S enantiomer and the metabolites are presumed to contribute only a little to the activity of the drug, in-depth side-by-side studies are lacking. The aim of this study...
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Main Authors: | , , , , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
American Society for Microbiology
2014
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4135865/ https://ncbi.nlm.nih.gov/pubmed/24982093 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02741-14 |
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