טוען...

In vitro and in vivo activity of R- and S- praziquantel enantiomers and the main human metabolite trans-4-hydroxy-praziquantel against Schistosoma haematobium

BACKGROUND: Praziquantel (PZQ) is the mainstay of schistosomiasis control and has been successfully used for decades. However, its mechanism of action is not fully understood. While the majority of studies have been conducted on Schistosoma mansoni, it is not known which enantiomer, R- or S-praziqua...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:Parasit Vectors
Main Authors: Kovač, Jana, Vargas, Mireille, Keiser, Jennifer
פורמט: Artigo
שפה:Inglês
יצא לאור: BioMed Central 2017
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC5540299/
https://ncbi.nlm.nih.gov/pubmed/28764732
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13071-017-2293-3
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