Aryl hydantoin Ro 13-3978, a broad-spectrum antischistosomal

OBJECTIVES: Praziquantel is the only drug available for the treatment of schistosomiasis and the state of the exhausted drug discovery pipeline is alarming. We restarted investigations on the abandoned antischistosomal Ro 13-3978, an aryl hydantoin discovered in the early 1980s by Hoffmann La-Roche....

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Publicat a:J Antimicrob Chemother
Autors principals: Keiser, Jennifer, Panic, Gordana, Vargas, Mireille, Wang, Chunkai, Dong, Yuxiang, Gautam, Nagsen, Vennerstrom, Jonathan L.
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2015
Matèries:
Original Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4462663/
https://ncbi.nlm.nih.gov/pubmed/25691324
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jac/dkv016
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