Differential repair of etheno-DNA adducts by bacterial and human AlkB proteins

AlkB proteins are evolutionary conserved Fe(II)/2-oxoglutarate-dependent dioxygenases, which remove alkyl and highly promutagenic etheno (ε)-DNA adducts, but their substrate specificity has not been fully determined. We developed a novel assay for the repair of ε-adducts by AlkB enzymes using oligod...

Celý popis

Uloženo v:
Podrobná bibliografie
Vydáno v:DNA Repair (Amst)
Hlavní autoři: Zdżalik, Daria, Domańska, Anna, Prorok, Paulina, Kosicki, Konrad, van den Born, Erwin, Falnes, Pål Ø., Rizzo, Carmelo J., Guengerich, F. Peter, Tudek, Barbara
Médium: Artigo
Jazyk:Inglês
Vydáno: 2015
Témata:
Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4451939/
https://ncbi.nlm.nih.gov/pubmed/25797601
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.dnarep.2015.02.021
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky