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Differential repair of etheno-DNA adducts by bacterial and human AlkB proteins
AlkB proteins are evolutionary conserved Fe(II)/2-oxoglutarate-dependent dioxygenases, which remove alkyl and highly promutagenic etheno (ε)-DNA adducts, but their substrate specificity has not been fully determined. We developed a novel assay for the repair of ε-adducts by AlkB enzymes using oligod...
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| Publicado en: | DNA Repair (Amst) |
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| Autores principales: | , , , , , , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2015
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4451939/ https://ncbi.nlm.nih.gov/pubmed/25797601 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.dnarep.2015.02.021 |
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