Llwytho...
Mechanism of Repair of Acrolein- and Malondialdehyde-Derived Exocyclic Guanine Adducts by the α-Ketoglutarate/Fe(II) Dioxygenase AlkB
[Image: see text] The structurally related exocyclic guanine adducts α-hydroxypropano-dG (α-OH-PdG), γ-hydroxypropano-dG (γ-OH-PdG), and M(1)dG are formed when DNA is exposed to the reactive aldehydes acrolein and malondialdehyde (MDA). These lesions are believed to form the basis for the observed c...
Wedi'i Gadw mewn:
| Prif Awduron: | , , , , , , , , |
|---|---|
| Fformat: | Artigo |
| Iaith: | Inglês |
| Cyhoeddwyd: |
American Chemical
Society
2014
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| Mynediad Ar-lein: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4164229/ https://ncbi.nlm.nih.gov/pubmed/25157679 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/tx5002817 |
| Tagiau: |
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