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Mutagenic potential of DNA–peptide crosslinks mediated by acrolein-derived DNA adducts

Current data suggest that DNA–peptide crosslinks are formed in cellular DNA as likely intermediates in the repair of DNA–protein crosslinks. In addition, a number of naturally occurring peptides are known to efficiently conjugate with DNA, particularly through the formation of Schiff-base complexes...

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Detalhes bibliográficos
Main Authors: Minko, Irina G., Kozekov, Ivan D., Kozekova, Albena, Harris, Thomas M., Rizzo, Carmelo J., Lloyd, R. Stephen
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3181171/
https://ncbi.nlm.nih.gov/pubmed/17868748
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mrfmmm.2007.08.001
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