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Spectroscopic Characterization of Interstrand Carbinolamine Crosslinks Formed in the 5'-CpG-3' Sequence by the Acrolein-Derived γ-OH-1,N(2)-Propano-2'-deoxyguanosine DNA Adduct
The interstrand N(2),N(2)-dG DNA crosslinking chemistry of the acrolein-derived γ-OH-1,N(2)-propanodeoxyguanosine (γ-OH-PdG) adduct in the 5'-CpG-3' sequence was monitored within a dodecamer duplex by NMR spectroscopy, in situ, using a series of site-specific (13)C- and (15)N-edited experi...
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| Main Authors: | , , , , , , , , , , , , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2005
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2631571/ https://ncbi.nlm.nih.gov/pubmed/16351098 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja053897e |
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