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Replication Bypass of the Acrolein-Mediated Deoxyguanine DNA–Peptide Cross-links by DNA polymerases of the DinB Family
DNA–protein cross-links (adducts) are formed in cellular DNA under a variety of conditions, particularly following exposure to an α,β-unsaturated aldehyde, acrolein. DNA–protein cross-links are subject to repair or damage-tolerance processes. These adducts serve as substrates for proteolytic degrada...
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| Main Authors: | , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2673917/ https://ncbi.nlm.nih.gov/pubmed/18788757 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/tx800174a |
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