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Role of High-Fidelity Escherichia coli DNA Polymerase I in Replication Bypass of a Deoxyadenosine DNA-Peptide Cross-Link

Reaction of bifunctional electrophiles with DNA in the presence of peptides can result in DNA-peptide cross-links. In particular, the linkage can be formed in the major groove of DNA via the exocyclic amino group of adenine (N(6)-dA). We previously demonstrated that an A family human polymerase, Pol...

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Detalhes bibliográficos
Main Authors: Yamanaka, Kinrin, Minko, Irina G., Finkel, Steven E., Goodman, Myron F., Lloyd, R. Stephen
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3147505/
https://ncbi.nlm.nih.gov/pubmed/21622737
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.01550-10
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