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Replication bypass of N(2)-deoxyguanosine interstrand cross-links by human DNA polymerases η and ι
DNA-interstrand cross-links (ICLs) can be repaired by biochemical pathways requiring DNA polymerases that are capable of translesion DNA synthesis (TLS). The anticipated function of TLS polymerases in these pathways is to insert nucleotides opposite and beyond the linkage site. The outcome of these...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3723381/ https://ncbi.nlm.nih.gov/pubmed/22332732 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/tx300011w |
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