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Replication bypass of N(2)-deoxyguanosine interstrand cross-links by human DNA polymerases η and ι
DNA-interstrand cross-links (ICLs) can be repaired by biochemical pathways requiring DNA polymerases that are capable of translesion DNA synthesis (TLS). The anticipated function of TLS polymerases in these pathways is to insert nucleotides opposite and beyond the linkage site. The outcome of these...
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| 主要な著者: | , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2012
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3723381/ https://ncbi.nlm.nih.gov/pubmed/22332732 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/tx300011w |
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