Replication Bypass of the Acrolein-Mediated Deoxyguanine DNA–Peptide Cross-links by DNA polymerases of the DinB Family

DNA–protein cross-links (adducts) are formed in cellular DNA under a variety of conditions, particularly following exposure to an α,β-unsaturated aldehyde, acrolein. DNA–protein cross-links are subject to repair or damage-tolerance processes. These adducts serve as substrates for proteolytic degrada...

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Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Minko, Irina G., Yamanaka, Kinrin, Kozekov, Ivan D., Kozekova, Albena, Indiani, Chiara, O’Donnell, Michael E., Jiang, Qingfei, Goodman, Myron F., Rizzo, Carmelo J., Lloyd, R. Stephen
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2008
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2673917/
https://ncbi.nlm.nih.gov/pubmed/18788757
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/tx800174a
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