AlkB Dioxygenase Preferentially Repairs Protonated Substrates: SPECIFICITY AGAINST EXOCYCLIC ADDUCTS AND MOLECULAR MECHANISM OF ACTION

Efficient repair by Escherichia coli AlkB dioxygenase of exocyclic DNA adducts 3,N(4)-ethenocytosine, 1,N(6)-ethenoadenine, 3,N(4)-α-hydroxyethanocytosine, and reported here for the first time 3,N(4)-α-hydroxypropanocytosine requires higher Fe(II) concentration than the reference 3-methylcytosine. T...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Päätekijät: Maciejewska, Agnieszka M., Poznański, Jarosław, Kaczmarska, Zuzanna, Krowisz, Beata, Nieminuszczy, Jadwiga, Polkowska-Nowakowska, Agnieszka, Grzesiuk, Elżbieta, Kuśmierek, Jarosław T.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society for Biochemistry and Molecular Biology 2013
Aiheet:
DNA and Chromosomes
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3537041/
https://ncbi.nlm.nih.gov/pubmed/23148216
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.353342
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