Novel AlkB Dioxygenases—Alternative Models for In Silico and In Vivo Studies

BACKGROUND: ALKBH proteins, the homologs of Escherichia coli AlkB dioxygenase, constitute a direct, single-protein repair system, protecting cellular DNA and RNA against the cytotoxic and mutagenic activity of alkylating agents, chemicals significantly contributing to tumor formation and used in can...

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Detalhes bibliográficos
Main Authors: Mielecki, Damian, Zugaj, Dorota Ł., Muszewska, Anna, Piwowarski, Jan, Chojnacka, Aleksandra, Mielecki, Marcin, Nieminuszczy, Jadwiga, Grynberg, Marcin, Grzesiuk, Elżbieta
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3265494/
https://ncbi.nlm.nih.gov/pubmed/22291995
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0030588
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