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The AlkB Family of Fe(II)/α-Ketoglutarate-dependent Dioxygenases: Repairing Nucleic Acid Alkylation Damage and Beyond

The AlkB family of Fe(II)- and α-ketoglutarate-dependent dioxygenases is a class of ubiquitous direct reversal DNA repair enzymes that remove alkyl adducts from nucleobases by oxidative dealkylation. The prototypical and homonymous family member is an Escherichia coli “adaptive response” protein tha...

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Detalles Bibliográficos
Publicado en:J Biol Chem
Main Authors: Fedeles, Bogdan I., Singh, Vipender, Delaney, James C., Li, Deyu, Essigmann, John M.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2015
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4543635/
https://ncbi.nlm.nih.gov/pubmed/26152727
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.R115.656462
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