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Selective phosphorylation modulates the PIP2 sensitivity of the CaM-SK channel complex
Phosphatidylinositol bisphosphate (PIP(2)) regulates the activities of many membrane proteins including ion channels through direct interactions. However, the affinity of PIP(2) is so high for some channel proteins that its physiological role as a modulator has been questioned. Here we show that PIP...
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| Publicado en: | Nat Chem Biol |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2014
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4420199/ https://ncbi.nlm.nih.gov/pubmed/25108821 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nchembio.1592 |
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