Selective phosphorylation modulates the PIP2 sensitivity of the CaM-SK channel complex

Phosphatidylinositol bisphosphate (PIP(2)) regulates the activities of many membrane proteins including ion channels through direct interactions. However, the affinity of PIP(2) is so high for some channel proteins that its physiological role as a modulator has been questioned. Here we show that PIP...

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Detaylı Bibliyografya
Yayımlandı:Nat Chem Biol
Asıl Yazarlar: Zhang, Miao, Meng, Xuan-Yu, Cui, Meng, Pascal, John M., Logothetis, Diomedes E., Zhang, Ji-Fang
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2014
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Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4420199/
https://ncbi.nlm.nih.gov/pubmed/25108821
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nchembio.1592
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