Diverse Phenotypes and Specific Transcription Patterns in Twenty Mouse Lines with Ablated LincRNAs

In a survey of 20 knockout mouse lines designed to examine the biological functions of large intergenic non-coding RNAs (lincRNAs), we have found a variety of phenotypes, ranging from perinatal lethality to defects associated with premature aging and morphological and functional abnormalities in the...

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Bibliografiset tiedot
Julkaisussa:PLoS One
Päätekijät: Lai, Ka-Man Venus, Gong, Guochun, Atanasio, Amanda, Rojas, José, Quispe, Joseph, Posca, Julita, White, Derek, Huang, Mei, Fedorova, Daria, Grant, Craig, Miloscio, Lawrence, Droguett, Gustavo, Poueymirou, William T., Auerbach, Wojtek, Yancopoulos, George D., Frendewey, David, Rinn, John, Valenzuela, David M.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Public Library of Science 2015
Aiheet:
Research Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4409293/
https://ncbi.nlm.nih.gov/pubmed/25909911
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0125522
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