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Diverse Phenotypes and Specific Transcription Patterns in Twenty Mouse Lines with Ablated LincRNAs

In a survey of 20 knockout mouse lines designed to examine the biological functions of large intergenic non-coding RNAs (lincRNAs), we have found a variety of phenotypes, ranging from perinatal lethality to defects associated with premature aging and morphological and functional abnormalities in the...

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Библиографические подробности
Опубликовано в: :PLoS One
Главные авторы: Lai, Ka-Man Venus, Gong, Guochun, Atanasio, Amanda, Rojas, José, Quispe, Joseph, Posca, Julita, White, Derek, Huang, Mei, Fedorova, Daria, Grant, Craig, Miloscio, Lawrence, Droguett, Gustavo, Poueymirou, William T., Auerbach, Wojtek, Yancopoulos, George D., Frendewey, David, Rinn, John, Valenzuela, David M.
Формат: Artigo
Язык:Inglês
Опубликовано: Public Library of Science 2015
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4409293/
https://ncbi.nlm.nih.gov/pubmed/25909911
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0125522
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