Diverse Phenotypes and Specific Transcription Patterns in Twenty Mouse Lines with Ablated LincRNAs

In a survey of 20 knockout mouse lines designed to examine the biological functions of large intergenic non-coding RNAs (lincRNAs), we have found a variety of phenotypes, ranging from perinatal lethality to defects associated with premature aging and morphological and functional abnormalities in the...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Lai, Ka-Man Venus, Gong, Guochun, Atanasio, Amanda, Rojas, José, Quispe, Joseph, Posca, Julita, White, Derek, Huang, Mei, Fedorova, Daria, Grant, Craig, Miloscio, Lawrence, Droguett, Gustavo, Poueymirou, William T., Auerbach, Wojtek, Yancopoulos, George D., Frendewey, David, Rinn, John, Valenzuela, David M.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4409293/
https://ncbi.nlm.nih.gov/pubmed/25909911
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0125522
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