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Enhancers in the Peril lincRNA locus regulate distant but not local genes

BACKGROUND: Recently, it has become clear that some promoters function as long-range regulators of gene expression. However, direct and quantitative assessment of enhancer activity at long intergenic noncoding RNA (lincRNA) or mRNA gene bodies has not been performed. To unbiasedly assess the enhance...

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Foilsithe in:Genome Biol
Main Authors: Groff, Abigail F., Barutcu, A. Rasim, Lewandowski, Jordan P., Rinn, John L.
Formáid: Artigo
Teanga:Inglês
Foilsithe: BioMed Central 2018
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6290506/
https://ncbi.nlm.nih.gov/pubmed/30537984
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13059-018-1589-8
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