Enhancers in the Peril lincRNA locus regulate distant but not local genes

BACKGROUND: Recently, it has become clear that some promoters function as long-range regulators of gene expression. However, direct and quantitative assessment of enhancer activity at long intergenic noncoding RNA (lincRNA) or mRNA gene bodies has not been performed. To unbiasedly assess the enhance...

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Bibliographic Details
Published in:Genome Biol
Main Authors: Groff, Abigail F., Barutcu, A. Rasim, Lewandowski, Jordan P., Rinn, John L.
Format: Artigo
Language:Inglês
Published: BioMed Central 2018
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Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6290506/
https://ncbi.nlm.nih.gov/pubmed/30537984
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13059-018-1589-8
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