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Enhancers in the Peril lincRNA locus regulate distant but not local genes

BACKGROUND: Recently, it has become clear that some promoters function as long-range regulators of gene expression. However, direct and quantitative assessment of enhancer activity at long intergenic noncoding RNA (lincRNA) or mRNA gene bodies has not been performed. To unbiasedly assess the enhance...

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Pubblicato in:Genome Biol
Autori principali: Groff, Abigail F., Barutcu, A. Rasim, Lewandowski, Jordan P., Rinn, John L.
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2018
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6290506/
https://ncbi.nlm.nih.gov/pubmed/30537984
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13059-018-1589-8
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