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Enhancers in the Peril lincRNA locus regulate distant but not local genes

BACKGROUND: Recently, it has become clear that some promoters function as long-range regulators of gene expression. However, direct and quantitative assessment of enhancer activity at long intergenic noncoding RNA (lincRNA) or mRNA gene bodies has not been performed. To unbiasedly assess the enhance...

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Detalhes bibliográficos
Publicado no:Genome Biol
Main Authors: Groff, Abigail F., Barutcu, A. Rasim, Lewandowski, Jordan P., Rinn, John L.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6290506/
https://ncbi.nlm.nih.gov/pubmed/30537984
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13059-018-1589-8
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