Diverse Phenotypes and Specific Transcription Patterns in Twenty Mouse Lines with Ablated LincRNAs

In a survey of 20 knockout mouse lines designed to examine the biological functions of large intergenic non-coding RNAs (lincRNAs), we have found a variety of phenotypes, ranging from perinatal lethality to defects associated with premature aging and morphological and functional abnormalities in the...

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Vydáno v:PLoS One
Hlavní autoři: Lai, Ka-Man Venus, Gong, Guochun, Atanasio, Amanda, Rojas, José, Quispe, Joseph, Posca, Julita, White, Derek, Huang, Mei, Fedorova, Daria, Grant, Craig, Miloscio, Lawrence, Droguett, Gustavo, Poueymirou, William T., Auerbach, Wojtek, Yancopoulos, George D., Frendewey, David, Rinn, John, Valenzuela, David M.
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2015
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4409293/
https://ncbi.nlm.nih.gov/pubmed/25909911
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0125522
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