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Chromatin environment, transcriptional regulation, and splicing distinguish lincRNAs and mRNAs

While long intergenic noncoding RNAs (lincRNAs) and mRNAs share similar biogenesis pathways, these transcript classes differ in many regards. LincRNAs are less evolutionarily conserved, less abundant, and more tissue-specific, suggesting that their pre- and post-transcriptional regulation is differe...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Genome Res
Hauptverfasser: Melé, Marta, Mattioli, Kaia, Mallard, William, Shechner, David M., Gerhardinger, Chiara, Rinn, John L.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Cold Spring Harbor Laboratory Press 2017
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5204342/
https://ncbi.nlm.nih.gov/pubmed/27927715
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.214205.116
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