Chromatin environment, transcriptional regulation, and splicing distinguish lincRNAs and mRNAs

While long intergenic noncoding RNAs (lincRNAs) and mRNAs share similar biogenesis pathways, these transcript classes differ in many regards. LincRNAs are less evolutionarily conserved, less abundant, and more tissue-specific, suggesting that their pre- and post-transcriptional regulation is differe...

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Bibliografiske detaljer
Udgivet i:Genome Res
Main Authors: Melé, Marta, Mattioli, Kaia, Mallard, William, Shechner, David M., Gerhardinger, Chiara, Rinn, John L.
Format: Artigo
Sprog:Inglês
Udgivet: Cold Spring Harbor Laboratory Press 2017
Fag:
Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5204342/
https://ncbi.nlm.nih.gov/pubmed/27927715
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.214205.116
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