The Novel Extracellular Cyclophilin A (CyPA) - Inhibitor MM284 Reduces Myocardial Inflammation and Remodeling in a Mouse Model of Troponin I -Induced Myocarditis

Cyclophilins are a group of highly conserved cytosolic enzymes that have a peptidylprolyl cis/trans isomerase activity. Cyclophilin A (CyPA) can be secreted in the extracellular space by inflammatory cells and upon cell death. The presence of CyPA in patients with non-ischemic cardiomyopathy is asso...

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Detaylı Bibliyografya
Yayımlandı:PLoS One
Asıl Yazarlar: Heinzmann, David, Bangert, Anna, Müller, Anna-Maria, von Ungern-Sternberg, Saskia N. I., Emschermann, Frederic, Schönberger, Tanja, Chatterjee, Madhumita, Mack, Andreas F., Klingel, Karin, Kandolf, Reinhard, Malesevic, Miroslav, Borst, Oliver, Gawaz, Meinrad, Langer, Harald F., Katus, Hugo, Fischer, Gunter, May, Andreas E., Kaya, Ziya, Seizer, Peter
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Public Library of Science 2015
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4404136/
https://ncbi.nlm.nih.gov/pubmed/25894208
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0124606
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