Cyclophilin A (CyPA) Induces Chemotaxis Independent of Its Peptidylprolyl Cis-Trans Isomerase Activity: DIRECT BINDING BETWEEN CyPA AND THE ECTODOMAIN OF CD147

Cyclophilin A (CyPA) is a ubiquitously distributed peptidylprolyl cis-trans isomerase (PPIase) that possesses diverse biological functions. Extracellular CyPA is a potent chemokine, which can directly induce leukocyte chemotaxis and contribute to the pathogenesis of inflammation-mediated diseases. A...

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Autori principali: Song, Fei, Zhang, Xin, Ren, Xiao-Bai, Zhu, Ping, Xu, Jing, Wang, Li, Li, Yi-Fei, Zhong, Nan, Ru, Qiang, Zhang, Da-Wei, Jiang, Jian-Li, Xia, Bin, Chen, Zhi-Nan
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Biochemistry and Molecular Biology 2011
Soggetti:
Molecular Bases of Disease
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3048706/
https://ncbi.nlm.nih.gov/pubmed/21245143
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.C110.181347
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