Extracellular cyclophilin A augments platelet-dependent thrombosis and thrombo-inflammation

Cyclophilin A (CyPA) is involved in the pathophysiology of several inflammatory and cardiovascular diseases. To our knowledge there is no specific inhibitor targeting extracellular CyPA without affecting other extracellular cyclophilins or intracellular CyPA functions. In this study we developed an...

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Publicado en:Thromb Haemost
Main Authors: von Ungern-Sternberg, Saskia N.I., Vogel, Sebastian, Walker-Allgaier, Britta, Geue, Sascha, Maurer, Andreas, Wild, Anna-Maria, Münzer, Patrick, Chatterjee, Madhumita, Heinzmann, David, Kremmer, Elisabeth, Borst, Oliver, Loughran, Patricia, Zernecke, Alma, Neal, Matthew D., Billiar, Timothy R., Gawaz, Meinrad, Seizer, Peter
Formato: Artigo
Idioma:Inglês
Publicado: 2017
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5885247/
https://ncbi.nlm.nih.gov/pubmed/28981554
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1160/TH17-01-0067
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