Extracellular cyclophilin A augments platelet-dependent thrombosis and thrombo-inflammation

Cyclophilin A (CyPA) is involved in the pathophysiology of several inflammatory and cardiovascular diseases. To our knowledge there is no specific inhibitor targeting extracellular CyPA without affecting other extracellular cyclophilins or intracellular CyPA functions. In this study we developed an...

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Publicat a:Thromb Haemost
Autors principals: von Ungern-Sternberg, Saskia N.I., Vogel, Sebastian, Walker-Allgaier, Britta, Geue, Sascha, Maurer, Andreas, Wild, Anna-Maria, Münzer, Patrick, Chatterjee, Madhumita, Heinzmann, David, Kremmer, Elisabeth, Borst, Oliver, Loughran, Patricia, Zernecke, Alma, Neal, Matthew D., Billiar, Timothy R., Gawaz, Meinrad, Seizer, Peter
Format: Artigo
Idioma:Inglês
Publicat: 2017
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5885247/
https://ncbi.nlm.nih.gov/pubmed/28981554
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1160/TH17-01-0067
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