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Stabilization of G protein-coupled receptors by point mutations

G protein-coupled receptors (GPCRs) are flexible integral membrane proteins involved in transmembrane signaling. Their involvement in many physiological processes makes them interesting targets for drug development. Determination of the structure of these receptors will help to design more specific...

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Bibliografski detalji
Izdano u:Front Pharmacol
Glavni autori: Heydenreich, Franziska M., Vuckovic, Ziva, Matkovic, Milos, Veprintsev, Dmitry B.
Format: Artigo
Jezik:Inglês
Izdano: Frontiers Media S.A. 2015
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4403299/
https://ncbi.nlm.nih.gov/pubmed/25941489
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2015.00082
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