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Large-scale production and protein engineering of G protein-coupled receptors for structural studies

Structural studies of G protein-coupled receptors (GPCRs) gave insights into molecular mechanisms of their action and contributed significantly to molecular pharmacology. This is primarily due to technical advances in protein engineering, production and crystallization of these important receptor ta...

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Detalhes bibliográficos
Publicado no:Front Pharmacol
Main Authors: Milić, Dalibor, Veprintsev, Dmitry B.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4379943/
https://ncbi.nlm.nih.gov/pubmed/25873898
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2015.00066
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