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Large-scale production and protein engineering of G protein-coupled receptors for structural studies

Structural studies of G protein-coupled receptors (GPCRs) gave insights into molecular mechanisms of their action and contributed significantly to molecular pharmacology. This is primarily due to technical advances in protein engineering, production and crystallization of these important receptor ta...

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Publicat a:Front Pharmacol
Autors principals: Milić, Dalibor, Veprintsev, Dmitry B.
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2015
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4379943/
https://ncbi.nlm.nih.gov/pubmed/25873898
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2015.00066
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