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Large-scale production and protein engineering of G protein-coupled receptors for structural studies

Structural studies of G protein-coupled receptors (GPCRs) gave insights into molecular mechanisms of their action and contributed significantly to molecular pharmacology. This is primarily due to technical advances in protein engineering, production and crystallization of these important receptor ta...

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Bibliografske podrobnosti
izdano v:Front Pharmacol
Main Authors: Milić, Dalibor, Veprintsev, Dmitry B.
Format: Artigo
Jezik:Inglês
Izdano: Frontiers Media S.A. 2015
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4379943/
https://ncbi.nlm.nih.gov/pubmed/25873898
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2015.00066
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