A versatile modular vector system for rapid combinatorial mammalian genetics

Here, we describe the multiple lentiviral expression (MuLE) system that allows multiple genetic alterations to be introduced simultaneously into mammalian cells. We created a toolbox of MuLE vectors that constitute a flexible, modular system for the rapid engineering of complex polycistronic lentivi...

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Dades bibliogràfiques
Publicat a:J Clin Invest
Autors principals: Albers, Joachim, Danzer, Claudia, Rechsteiner, Markus, Lehmann, Holger, Brandt, Laura P., Hejhal, Tomas, Catalano, Antonella, Busenhart, Philipp, Gonçalves, Ana Filipa, Brandt, Simone, Bode, Peter K., Bode-Lesniewska, Beata, Wild, Peter J., Frew, Ian J.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Clinical Investigation 2015
Matèries:
Technical Advance
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4396471/
https://ncbi.nlm.nih.gov/pubmed/25751063
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI79743
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