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Mouse genetic background influences whether Hras(G12V) expression plus Cdkn2a knockdown causes angiosarcoma or undifferentiated pleomorphic sarcoma

Soft tissue sarcomas are rare mesenchymal tumours accounting for 1% of adult malignancies and are fatal in approximately one third of patients. Two of the most aggressive and lethal forms of soft tissue sarcomas are angiosarcomas and undifferentiated pleomorphic sarcomas (UPS). To examine sarcoma-re...

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Библиографические подробности
Опубликовано в: :Oncotarget
Главные авторы: Brandt, Laura P., Albers, Joachim, Hejhal, Tomas, Pfundstein, Svende, Gonçalves, Ana Filipa, Catalano, Antonella, Wild, Peter J., Frew, Ian J.
Формат: Artigo
Язык:Inglês
Опубликовано: Impact Journals LLC 2018
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5929423/
https://ncbi.nlm.nih.gov/pubmed/29731980
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.24831
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