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Mouse genetic background influences whether Hras(G12V) expression plus Cdkn2a knockdown causes angiosarcoma or undifferentiated pleomorphic sarcoma

Soft tissue sarcomas are rare mesenchymal tumours accounting for 1% of adult malignancies and are fatal in approximately one third of patients. Two of the most aggressive and lethal forms of soft tissue sarcomas are angiosarcomas and undifferentiated pleomorphic sarcomas (UPS). To examine sarcoma-re...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Brandt, Laura P., Albers, Joachim, Hejhal, Tomas, Pfundstein, Svende, Gonçalves, Ana Filipa, Catalano, Antonella, Wild, Peter J., Frew, Ian J.
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5929423/
https://ncbi.nlm.nih.gov/pubmed/29731980
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.24831
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