Sensitivity and Resistance of Oncogenic RAS-Driven Tumors to Dual MEK and ERK Inhibition

SIMPLE SUMMARY: Mutations in RAS-family genes frequently cause different types of human cancers. Inhibitors of the MEK (mitogen-activated protein kinase) and ERK (extracellular signal-regulated kinase) protein kinases that function downstream of RAS proteins have shown some clinical benefits when us...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Cancers (Basel)
Main Authors: Catalano, Antonella, Adlesic, Mojca, Kaltenbacher, Thorsten, Klar, Rhena F. U., Albers, Joachim, Seidel, Philipp, Brandt, Laura P., Hejhal, Tomas, Busenhart, Philipp, Röhner, Niklas, Zodel, Kyra, Fritsch, Kornelia, Wild, Peter J., Duyster, Justus, Fritsch, Ralph, Brummer, Tilman, Frew, Ian J.
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2021
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8069437/
https://ncbi.nlm.nih.gov/pubmed/33924486
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers13081852
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados