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Cdk4 functions in multiple cell types to control Drosophila intestinal stem cell proliferation and differentiation

The proliferation of intestinal stem cells (ISCs) and differentiation of enteroblasts to form mature enteroendocrine cells and enterocytes in the Drosophila intestinal epithelium must be tightly regulated to maintain homeostasis. We show that genetic modulation of CyclinD/Cdk4 activity or mTOR-depen...

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Detalhes bibliográficos
Publicado no:Biol Open
Main Authors: Adlesic, Mojca, Frei, Christian, Frew, Ian J.
Formato: Artigo
Idioma:Inglês
Publicado em: The Company of Biologists Ltd 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4810749/
https://ncbi.nlm.nih.gov/pubmed/26879465
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/bio.016584
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