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Combined Deletion of Vhl and Kif3a Accelerates Renal Cyst Formation
A subset of familial and sporadic clear cell renal cell carcinomas (ccRCCs) is believed to develop from cystic precursor lesions. Loss of function of the von Hippel-Lindau tumor suppressor gene (VHL) predisposes renal epithelial cells to loss of the primary cilium in response to specific signals. Be...
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| Publicado no: | J Am Soc Nephrol |
|---|---|
| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society of Nephrology
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4625677/ https://ncbi.nlm.nih.gov/pubmed/25788526 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2014090875 |
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