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pVHL and PTEN tumour suppressor proteins cooperatively suppress kidney cyst formation
In patients with von Hippel–Lindau (VHL) disease, renal cysts and clear cell renal cell carcinoma (ccRCC) arise from renal tubular epithelial cells containing biallelic inactivation of the VHL tumour suppressor gene. However, it is presumed that formation of renal cysts and their conversion to ccRCC...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2435131/ https://ncbi.nlm.nih.gov/pubmed/18497742 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2008.96 |
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