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Combined Vhlh and Pten Mutation Causes Genital Tract Cystadenoma and Squamous Metaplasia

Patients with von Hippel-Lindau (VHL) disease develop tumors in a range of tissues, but existing mouse models of Vhlh mutation have failed to reproduce these lesions. Epididymal cystadenomas arise frequently in VHL patients, but VHL mutation alone is believed to be insufficient for tumor formation,...

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Detalhes bibliográficos
Main Authors: Frew, Ian J., Minola, Andrea, Georgiev, Strahil, Hitz, Manuela, Moch, Holger, Richard, Stéphane, Vortmeyer, Alexander O., Krek, Wilhelm
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2447121/
https://ncbi.nlm.nih.gov/pubmed/18474617
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.02132-07
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