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Priming-Dependent Phosphorylation and Regulation of the Tumor Suppressor pVHL by Glycogen Synthase Kinase 3

Inactivation of the von Hippel-Lindau (VHL) tumor suppressor gene is linked to the development of tumors of the eyes, kidneys, and central nervous system. VHL encodes two gene products, pVHL(30) and pVHL(19), of which one, pVHL(30), associates functionally with microtubules (MTs) to regulate their s...

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Detalhes bibliográficos
Main Authors: Hergovich, Alexander, Lisztwan, Joanna, Thoma, Claudio R., Wirbelauer, Christiane, Barry, Robert E., Krek, Wilhelm
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2006
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1592755/
https://ncbi.nlm.nih.gov/pubmed/16847331
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00232-06
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