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Co-clinical assessment identifies patterns of BRAF inhibitor resistance in melanoma

Multiple mechanisms have been described that confer BRAF inhibitor resistance to melanomas, yet the basis of this resistance remains undefined in a sizable portion of patient samples. Here, we characterized samples from a set of patients with melanoma that included individuals at baseline diagnosis,...

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Detalhes bibliográficos
Publicado no:J Clin Invest
Main Authors: Kwong, Lawrence N., Boland, Genevieve M., Frederick, Dennie T., Helms, Timothy L., Akid, Ahmad T., Miller, John P., Jiang, Shan, Cooper, Zachary A., Song, Xingzhi, Seth, Sahil, Kamara, Jennifer, Protopopov, Alexei, Mills, Gordon B., Flaherty, Keith T., Wargo, Jennifer A., Chin, Lynda
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4396463/
https://ncbi.nlm.nih.gov/pubmed/25705882
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI78954
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