Co-clinical assessment identifies patterns of BRAF inhibitor resistance in melanoma

Multiple mechanisms have been described that confer BRAF inhibitor resistance to melanomas, yet the basis of this resistance remains undefined in a sizable portion of patient samples. Here, we characterized samples from a set of patients with melanoma that included individuals at baseline diagnosis,...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Τόπος έκδοσης:J Clin Invest
Κύριοι συγγραφείς: Kwong, Lawrence N., Boland, Genevieve M., Frederick, Dennie T., Helms, Timothy L., Akid, Ahmad T., Miller, John P., Jiang, Shan, Cooper, Zachary A., Song, Xingzhi, Seth, Sahil, Kamara, Jennifer, Protopopov, Alexei, Mills, Gordon B., Flaherty, Keith T., Wargo, Jennifer A., Chin, Lynda
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: American Society for Clinical Investigation 2015
Θέματα:
Research Article
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4396463/
https://ncbi.nlm.nih.gov/pubmed/25705882
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI78954
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