Co-clinical assessment identifies patterns of BRAF inhibitor resistance in melanoma

Multiple mechanisms have been described that confer BRAF inhibitor resistance to melanomas, yet the basis of this resistance remains undefined in a sizable portion of patient samples. Here, we characterized samples from a set of patients with melanoma that included individuals at baseline diagnosis,...

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Dades bibliogràfiques
Publicat a:J Clin Invest
Autors principals: Kwong, Lawrence N., Boland, Genevieve M., Frederick, Dennie T., Helms, Timothy L., Akid, Ahmad T., Miller, John P., Jiang, Shan, Cooper, Zachary A., Song, Xingzhi, Seth, Sahil, Kamara, Jennifer, Protopopov, Alexei, Mills, Gordon B., Flaherty, Keith T., Wargo, Jennifer A., Chin, Lynda
Format: Artigo
Idioma:Inglês
Publicat: American Society for Clinical Investigation 2015
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4396463/
https://ncbi.nlm.nih.gov/pubmed/25705882
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI78954
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