Co-clinical assessment identifies patterns of BRAF inhibitor resistance in melanoma

Multiple mechanisms have been described that confer BRAF inhibitor resistance to melanomas, yet the basis of this resistance remains undefined in a sizable portion of patient samples. Here, we characterized samples from a set of patients with melanoma that included individuals at baseline diagnosis,...

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Bibliografiske detaljer
Udgivet i:J Clin Invest
Main Authors: Kwong, Lawrence N., Boland, Genevieve M., Frederick, Dennie T., Helms, Timothy L., Akid, Ahmad T., Miller, John P., Jiang, Shan, Cooper, Zachary A., Song, Xingzhi, Seth, Sahil, Kamara, Jennifer, Protopopov, Alexei, Mills, Gordon B., Flaherty, Keith T., Wargo, Jennifer A., Chin, Lynda
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Clinical Investigation 2015
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4396463/
https://ncbi.nlm.nih.gov/pubmed/25705882
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI78954
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