Co-clinical assessment identifies patterns of BRAF inhibitor resistance in melanoma

Multiple mechanisms have been described that confer BRAF inhibitor resistance to melanomas, yet the basis of this resistance remains undefined in a sizable portion of patient samples. Here, we characterized samples from a set of patients with melanoma that included individuals at baseline diagnosis,...

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Vydáno v:J Clin Invest
Hlavní autoři: Kwong, Lawrence N., Boland, Genevieve M., Frederick, Dennie T., Helms, Timothy L., Akid, Ahmad T., Miller, John P., Jiang, Shan, Cooper, Zachary A., Song, Xingzhi, Seth, Sahil, Kamara, Jennifer, Protopopov, Alexei, Mills, Gordon B., Flaherty, Keith T., Wargo, Jennifer A., Chin, Lynda
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Clinical Investigation 2015
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4396463/
https://ncbi.nlm.nih.gov/pubmed/25705882
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI78954
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