30S Subunit-Dependent Activation of the Sorangium cellulosum So ce56 Aminoglycoside Resistance-Conferring 16S rRNA Methyltransferase Kmr

Methylation of bacterial 16S rRNA within the ribosomal decoding center confers exceptionally high resistance to aminoglycoside antibiotics. This resistance mechanism is exploited by aminoglycoside producers for self-protection while functionally equivalent methyltransferases have been acquired by hu...

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Bibliografiske detaljer
Udgivet i:Antimicrob Agents Chemother
Main Authors: Savic, Miloje, Sunita, S., Zelinskaya, Natalia, Desai, Pooja M., Macmaster, Rachel, Vinal, Kellie, Conn, Graeme L.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2015
Fag:
Mechanisms of Resistance
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4394793/
https://ncbi.nlm.nih.gov/pubmed/25733511
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00056-15
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