Substrate Recognition and Modification by a Pathogen-Associated Aminoglycoside Resistance 16S rRNA Methyltransferase

Por Vinal, Kellie, Conn, Graeme L.
Publicado no Antimicrob Agents Chemother (2017)

Analysis of adenovirus VA RNA(I) structure and stability using compensatory base pair modifications

Por Coventry, Veronica K., Conn, Graeme L.
Publicado em 2008

Expansion of the aminoglycoside-resistance 16S rRNA (m(1)A1408) methyltransferase family: expression and functional characterization of four hypothetical enzymes of diverse bacteri...

Por Witek, Marta A., Conn, Graeme L.
Publicado em 2014

Binding Induced RNA Conformational Changes Control Substrate Recognition and Catalysis by the Thiostrepton Resistance Methyltransferase (Tsr)

Por Kuiper, Emily G., Conn, Graeme L.
Publicado em 2014

Functional dichotomy in the 16S rRNA (m(1)A1408) methyltransferase family and control of catalytic activity via a novel tryptophan mediated loop reorganization

Por Witek, Marta A., Conn, Graeme L.
Publicado no Nucleic Acids Res (2016)

Human noncoding RNA 886 (nc886) adopts two structurally distinct conformers that are functionally opposing regulators of PKR

Por Calderon, Brenda M., Conn, Graeme L.
Publicado no RNA (2017)

The Regulatory and Kinase Domains but Not the Interdomain Linker Determine Human Double-stranded RNA-activated Kinase (PKR) Sensitivity to Inhibition by Viral Non-coding RNAs

Por Sunita, S., Schwartz, Samantha L., Conn, Graeme L.
Publicado no J Biol Chem (2015)

Optimization of a Ribosomal Structural Domain by Natural Selection

Por Maeder, Corina, Conn, Graeme L., Draper, David E.
Publicado em 2006

The Pathogen-Derived Aminoglycoside Resistance 16S rRNA Methyltransferase NpmA Possesses Dual m(1)A1408/m(1)G1408 Specificity

Por Zelinskaya, Natalia, Witek, Marta A., Conn, Graeme L.
Publicado no Antimicrob Agents Chemother (2015)

General plasmids for producing RNA in vitro transcripts with homogeneous ends

Por Walker, Scott C., Avis, Johanna M., Conn, Graeme L.
Publicado em 2003

Systematic Deletion of the Adenovirus-associated RNA(I) Terminal Stem Reveals a Surprisingly Active RNA Inhibitor of Double-stranded RNA-activated Protein Kinase

Por Wahid, Ahmed M., Coventry, Veronica K., Conn, Graeme L.
Publicado em 2008

The PKR-binding domain of adenovirus VA RNA(I) exists as a mixture of two functionally non-equivalent structures

Por Wahid, Ahmed M., Coventry, Veronica K., Conn, Graeme L.
Publicado em 2009

A novel RNA molecular signature for activation of 2′-5′ oligoadenylate synthetase-1

Por Vachon, Virginia K., Calderon, Brenda M., Conn, Graeme L.
Publicado no Nucleic Acids Res (2015)

Aminoglycoside resistance genes sgm and kgmB protect bacterial but not yeast small ribosomal subunits in vitro despite high conservation of the rRNA A-site

Por Tomic, Tatjana Ilic, Moric, Ivana, Conn, Graeme L., Vasiljevic, Branka
Publicado em 2008

Raman and Raman optical activity (ROA) analysis of RNA structural motifs in Domain I of the EMCV IRES

Por Hobro, Alison J., Rouhi, Mansour, Blanch, Ewan W., Conn, Graeme L.
Publicado em 2007

Conserved Nucleotides within the J Domain of the Encephalomyocarditis Virus Internal Ribosome Entry Site Are Required for Activity and for Interaction with eIF4G

Por Clark, Angela T., Robertson, Morwenna E. M., Conn, Graeme L., Belsham, Graham J.
Publicado em 2003

Critical Residues for Cofactor Binding and Catalytic Activity in the Aminoglycoside Resistance Methyltransferase Sgm

Por Savic, Miloje, Ilic-Tomic, Tatjana, Macmaster, Rachel, Vasiljevic, Branka, Conn, Graeme L.
Publicado em 2008

Determination of the target nucleosides for members of two families of 16S rRNA methyltransferases that confer resistance to partially overlapping groups of aminoglycoside antibiot...

Por Savic, Miloje, Lovrić, Josip, Tomic, Tatjana Ilic, Vasiljevic, Branka, Conn, Graeme L.
Publicado em 2009

Structural insights into the function of aminoglycoside-resistance A1408 16S rRNA methyltransferases from antibiotic-producing and human pathogenic bacteria

Por Macmaster, Rachel, Zelinskaya, Natalia, Savic, Miloje, Rankin, C. Robert, Conn, Graeme L.
Publicado em 2010

Expression, purification and crystallization of adenosine 1408 aminoglycoside-resistance rRNA methyltransferases for structural studies

Por Zelinskaya, Natalia, Rankin, C. Robert, Macmaster, Rachel, Savic, Miloje, Conn, Graeme L.
Publicado em 2010