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A novel RNA molecular signature for activation of 2′-5′ oligoadenylate synthetase-1
Human 2′-5′ oligoadenylate synthetase-1 (OAS1) is central in innate immune system detection of cytoplasmic double-stranded RNA (dsRNA) and promotion of host antiviral responses. However, the molecular signatures that promote OAS1 activation are currently poorly defined. We show that the 3′-end polyu...
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| Publicado no: | Nucleic Acids Res |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4288181/ https://ncbi.nlm.nih.gov/pubmed/25477390 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gku1289 |
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