Loading...
Nucleoside modifications in RNA limit activation of 2′-5′-oligoadenylate synthetase and increase resistance to cleavage by RNase L
The interferon-induced enzymes 2′-5′-oligoadenylate synthetase (OAS) and RNase L are key components of innate immunity involved in sensory and effector functions following viral infections. Upon binding target RNA, OAS is activated to produce 2′-5′-linked oligoadenylates (2-5A) that activate RNase L...
Na minha lista:
| Main Authors: | , , , , , |
|---|---|
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Oxford University Press
2011
|
| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3241635/ https://ncbi.nlm.nih.gov/pubmed/21813458 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkr586 |
| Tags: |
Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!
|