Viral Encounters with 2′,5′-Oligoadenylate Synthetase and RNase L during the Interferon Antiviral Response

Eitemau Tebyg

• Nucleoside modifications in RNA limit activation of 2′-5′-oligoadenylate synthetase and increase resistance to cleavage by RNase L
  gan: Anderson, Bart R., et al.
  Cyhoeddwyd: (2011)
• The 2′-5′-Oligoadenylate Synthetase 3 Enzyme Potently Synthesizes the 2′-5′-Oligoadenylates Required for RNase L Activation
  gan: Ibsen, Mikkel Søes, et al.
  Cyhoeddwyd: (2014)
• Interferon action and apoptosis are defective in mice devoid of 2',5'-oligoadenylate-dependent RNase L.
  gan: Zhou, A, et al.
  Cyhoeddwyd: (1997)
• Studies on the role of the 2'-5'-oligoadenylate synthetase-RNase L pathway in beta interferon-mediated inhibition of encephalomyocarditis virus replication.
  gan: Kumar, R, et al.
  Cyhoeddwyd: (1988)
• Structural Basis for 2′-5′-Oligoadenylate Binding and Enzyme Activity of a Viral RNase L Antagonist
  gan: Ogden, Kristen M., et al.
  Cyhoeddwyd: (2015)